DESCRIPTION

• Aa: 33-320
• Mw: 62 kDa
• Tags: C-terminal Fc-Avi-tag
• Format: Aqueous buffer solution
• Genbank: NM_ 014339
• Species: Human
• Uniprot: Q96F46
• Shiptemp: -80°C (dry ice)
• Synonyms: CD217, IL17R, IMD51, CANDF5, CDw217, hIL-17R
• Warnings: Avoid freeze/thaw cycles.
• Category: Cytokine
• References: 1. Wright, J.F., et. al. J. Immun. 2008; 181(4): 2799-2805.2. Rickel, E.A., et al., J. Immun. 2008; 181(6): 4299-4310.
• Description: Human Interleukin-17A (IL-17A), also known as CD217 and CANDF5, GenBank Accession No. NM_ 014339, a.a 33-320, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag™, expressed in a HEK293 cell expression system, MW=62 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
• Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
• Supplied As: Aqueous buffer solution.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and screening small molecules for drug discovery.
• Host Species: human
• Product Type: Protein
• Host Cell Line: HEK293
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: IL-17RA-IL-17A[B] binding activity was measured using the IL-17RA:IL-17A[Biotin] Binding Assay Kit, BPS Bioscience #79891 and Anti-IL-17A Antibody, BPS Bioscience #91015.
• Related Products: 91015, 91013, 91014, 79891
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy