RP01422
Recombinant Human Frizzled-2/FZD2 Protein
ABclonal
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DESCRIPTION
Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.
DETAILS
- Tag: C-hFc&His
- Source: HEK293 cells
- Gene Id: 2535
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: Q14332
- Research Areas: Other Recombinant Protein
- Alternative Names: Fz2, fz-2, fzE2, hFz2, OMOD2,FZD2
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