Human HTT Protein, MBP,His Tag (MALS verified)

DESCRIPTION

Huntingtin is the protein coded for by the HTT gene. Autosomal dominant mutation in the Huntingtin (Htt) protein is the cause of Huntington’s Disease (HD). In HD, the polyglutamine (polyQ) domain in the N-terminal sequenceof the protein is expanded beyond a threshold of 36 glutamines. mutant polyQ expansion strongly correlates in an inverse manner to disease age of onset.

DETAILS

Tag: N-MBP & C-10×His
Host: E. coli
Size: 25ug
Buffer: 20 mM HEPES, 150 mM NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Human HTT, MBP,His Tag (HTT-H51M5) is expressed from E. coli cells. It contains AA Met 1 - Glu 82 (Accession # P42858-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: HTT
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Met 1 - Glu 82
Swiss-prot: P42858-1
Package Size: 25ug*1
Characteristics: This protein carries a MBP tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.7 kDa. The protein migrates as 60-63 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 52.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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