Human 4-1BB Ligand / TNFSF9 (71-254) Protein, Fc Tag, active trimer, premium grade

DESCRIPTION

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

DETAILS

Tag: N-Fc
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human 4-1BB Ligand (71-254) Protein, Fc Tag, premium grade (41L-H5269) is expressed from human 293 cells (HEK293). It contains AA Arg 71 - Glu 254 (Accession # P41273-1).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: 4-1BB Ligand
Accession: NP_003802.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Arg 71 - Glu 254
Swiss-prot: P41273-1
Package Size: 500ug*2
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 87.5 kDa. The protein migrates as 95 kDa±5 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.01 EU per μg
Molecular Weight: 87.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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