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Animal-Free Recombinant Murine IL-3



IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.


  • Gene Id: 16187
  • Uniprot: P01586
  • Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse NFS-60 cells is ≤0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg.
  • Category: RUO Cytokines
  • Subcategory: Animal-Free Cytokines
  • Research Areas: AIDS/HIV, Cancer, Cell Culture, Diabetes/Weight Regulation, Immune System, Stem Cells and Differentiation
  • Alternative Names: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
  • Species of Origin: Murine
  • Expression System Source: E.coli