DESCRIPTION

• Notes: Troubleshooting Guide: Visit bpsbioscience.com/assay-kits-faq for detailed troubleshooting instructions. For all further questions, please email support@bpsbioscience.com.
• Uniprot: P22455
• Shiptemp: -80°C (dry ice)
• Synonyms: Fibroblast growth factor receptor 4, FGFR-4, CD334, JTK2, TKF
• Warnings: Avoid freeze/thaw cycles
• Category: Kinase/Assay Kit
• Background: FGFR4 (also known as CD334) is a transmembrane receptor with tyrosine kinase activity. The extracellular portion of the receptor contains three immunoglobulin-like domains and is responsible for binding fibroblast growth factor 1 (FGF1). It contains a single transmembrane domain followed by the cytosolic kinase domain. FGFR4 may be involved in ovarian cancer as well as adrenocortical carcinoma and is a promising therapeutic target in oncology applications.  
• Description: The Fibroblast growth factor receptor 4 (FGFR4) Kinase Assay Kit is designed to measure FGFR4 kinase activity for screening and profiling applications using ADP-Glo® as a detection reagent. 
• Supplied As: The assay kit comes in a convenient 96-well format, with enough purified recombinant FGFR4 kinase, kinase substrate, ATP and kinase assay buffer for 100 enzyme reactions.
• Unspsc Code: 41105332
• Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
• Applications: Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40213, 79804, 79818, 79819
• Contraindications: The final concentration of DMSO in the assay should not exceed 1%.
• Storage Stability: This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
• Scientific Category: Kinase