16352
KB-R7943 (mesylate)
Cayman Chemical
DESCRIPTION
A selective inhibitor of the reverse mode of NCX1 (IC50 = 1.2-2.4 µM) that prevents intracellular sodium-dependent calcium uptake in whole cells; exhibits neuroprotection from glutamate-induced excitotoxicity; inhibits TRPC channels involved in calcium-dependent signal transduction
DETAILS
- Inchi: InChI=1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Neuroscience
- Smiles: NC(SCCC(C=C1)=CC=C1OCC2=CC=C([N+]([O-])=O)C=C2)=N.OS(C)(=O)=O
- Inchikey: WGIKEBHIKKWJLG-UHFFFAOYSA-N
- Cas Number: 182004-65-5
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C16H17N3O3S • CH3SO3H
- Formula Weight: 427.5
- Shelf Life Days: 1460