DESCRIPTION

• Host: Rabbit
• Status: 2 Weeks*
• Gene Id: 1269
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
• Category: Antibodies
• Synonyms: CB-2, hCB2, CB2, CNR2, CX5
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human CB2.
• Stability: Shelf life: One year from despatch.
• Background: The cannabinoid receptors (CB1 and CB2) are G protein-coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids.CB1 is expressed in brain tissue and, in low levels, in testis. CB2 is expressed only by cells of the immune system. The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner. This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation, as well as having a possible role in brain development. In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana.
• Uniprot Id: P34972
• Conjugation: Unconjugated
• Formulation: Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). Preservative: 0.05% Sodium Azide
• Gene Symbol: CNR2
• Specificity: This antibody detects endogenous levels of Cannabinoid Receptor 2 (CB2) protein. (region surrounding Arg334)
• Applications: IF, WB
• Availability: 2 Weeks
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Reactivities: Human
• Concentration: 1.0 mg/ml
• Database Link: Entrez Gene 1269 Human UniProt ID P34972
• Recommended Dilution: Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
• Predicted Protein Size: ~ 40 kDa