TNPO1 Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 3842
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: TNPO1
Other Names: Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein, MIP, TNPO1, KPNB2, MIP1, TRN
Availability: 2 weeks
Bio Background: TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.
Bio References: Fineberg, K., et al., Biochemistry 42(9):2625-2633 (2003).Nelson, L.M., et al., Virology 306(1):162-169 (2003).Le Roux, L.G., et al., J. Virol. 77(4):2330-2337 (2003).Limon, A., et al., J. Virol. 76(21):10598-10607 (2002).Dvorin, J.D., et al., J. Virol. 76(23):12087-12096 (2002).
Primary Accession: Q92973
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1934e was selected from the N-term region of human TNPO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.