LGALS3BP Blocking Peptide (Center)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 3959
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: LGALS3BP
Other Names: Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP
Availability: 2 weeks
Bio Background: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Bio References: Davila, S., et al. Genes Immun. 11(3):232-238(2010) Srirajaskanthan, R., et al. Mol. Cell Proteomics 9(4):656-666(2010) Zambelli, D., et al. Int. J. Cancer 126(1):41-52(2010) Lee, J.H., et al. Pathology 41(3):229-233(2009) Kim, S.J., et al. Acta Haematol. 120(4):211-216(2008)
Other Accession: NP_005558.1
Primary Accession: Q08380
Targetspecificity: The synthetic peptide sequence is selected from aa 398-412 of HUMAN LGALS3BP