Recombinant Human Galectin-1

DESCRIPTION

Lectins, of either plant or animal origin, are carbohydrate-binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T cells and T leukemia cell lines, and inhibits the protein phosphatase activity of CD45. Recombinant Human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

DETAILS

Gene Id: 3956
Uniprot: P09382
Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: Apoptosis, Cancer, Immune System, Neurobiology, Stem Cells and Differentiation
Alternative Names: Galactose-specific lectin-1,beta-galactoside-binding lectin L-14-I, Galaptin, 14 kDa lectin, S-LAC lectin-1
Species of Origin: Human
Expression System Source: E.coli