1455-NFMt 1455-NFM
Promo Available
Anti-Neurofilament NF-M Antibody
PhosphoSolutions
DESCRIPTION
Our Anti-Neurofilament NF-M primary antibody from PhosphoSolutions is chicken polyclonal. It detects bovine, chicken, human, mouse, and rat Neurofilament NF-M and is total IgY fraction. It is great for use in WB, IHC, ICC.
DETAILS
- Form: Total IgY fraction
- Gene: NEFM
- Host: Chicken
- Rrid: AB_2492164
- Type: Primary Antibody
- Buffer: PBS + 10 mM NaN3.
- Target: Neurofilament NF-M
- Isotype: IgY
- Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
- Shipping: Blue Ice
- Synonyms: 150 kDa Neurofilament Medium antibody, 160 kDa neurofilament protein antibody, Medium polypeptide 150kDa antibody, NEF3 antibody, Neurofilament 3 antibody, Neurofilament 3 medium antibody, Neurofilament medium polypeptide antibody, Neurofilament protein M antibody, Neurofilament triplet M protein antibody, Neurofilament-3 (150 kD medium) antibody, NF-M antibody, NFM antibody
- Clonality: Polyclonal
- Immunogen: Preparation containing the extreme C-terminus of rat NF-M, expressed in and purified from E. Coli.
- Expiration: After date of receipt, stable for at least 1 year at -20°C.
- Specificity: Specific for endogenous levels of the ~145 kDa Neurofilament M protein.
- Applications: WB, IHC, ICC
- Ncbi Gene Id: 24588
- Conjugate Exem: Unconjugated
- Physical State: Liquid
- Quality Control: Western blots performed on each lot.
- Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
- Molecular Weight: 145
- Production Notes: Total IgY fraction
- Dilution Range Wb: 1:5000
- Immunogen Species: Rat
- Dilution Range Icc: 1:1000
- Dilution Range Ihc: 1:1000
- Species Reactivity: Bovine, Chicken, Human, Mouse, and Rat
- Target Description: Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (Harris et al., 1991). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (Hu et al., 2002).
- Dilution Range Wb Brain: 1:5000
- Uniprot Number Immunogen Species: P12839
PROMOTION TERMS
Trial Size Available. Limit 1