22066
PF-1163B
Cayman Chemical
DESCRIPTION
A depsipeptide antifungal; inhibits ERG synthesis (IC50 = 34 ng/ml); selectively inhibits growth of C. albicans (MIC = 32 µg/ml); acts synergistically with fluconazole to reduce growth of azole-resistant C. albicans (MIC = 0.0016 µg/ml); hydroxy form of PF-1163A
DETAILS
- Inchi: InChI=1S/C27H43NO5/c1-4-5-6-10-24-15-12-21(2)9-7-8-11-26(30)28(3)25(27(31)33-24)20-22-13-16-23(17-14-22)32-19-18-29/h13-14,16-17,21,24-25,29H,4-12,15,18-20H2,1-3H3/t21-,24-,25+/m1/s1
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Candidiasis
- Smiles: O=C(N(C)[C@H]1CC2=CC=C(OCCO)C=C2)CCCC[C@@H](C)CC[C@@H](CCCCC)OC1=O
- Inchikey: PCRJJAXIHTZHNU-SDUSCBPUSA-N
- Cas Number: 258871-60-2
- Formulation: An oil
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C27H43NO5
- Formula Weight: 461.6
- Shelf Life Days: 1460