E1564Hu
Scientist.com Supplier
Human Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
DETAILS
- Gene Id: 657
- Uniprot: P36894
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 0.045ng/mL
- Detection Range: 0.1-40ng/mL
- Detection Method: ELISA
- Species Reactivity: Human