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E1564Hu

Human Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

DETAILS

  • GeneID: 657
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 60,198
  • Synonyms: Activin receptor-like kinase 3;ALK-3;BMP type-1A receptor;BMPR 1A;BMPR1A;BMPR-1A;Bone morphogenetic protein receptor type-1A;CD antigen CD292;Serine/threonine-protein kinase receptor R5;SKR5
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: BMPR1A
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.045ng/mL
  • Target Protein: BMPR1A
  • Detection Range: 0.1-40ng/mL
  • Full Product Name: Bone Morphogenetic Protein Receptor 1A
  • Standard Solution: 48ng/mL
  • UniProt Accession: P36894