T38363
MeOSuc-AAPV-pNA
TargetMol
DESCRIPTION
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
DETAILS
- Cas: 70967-90-7
- Purity: 98%
- Smiles: C(N[C@H](C(NC1=CC=C(N(=O)=O)C=C1)=O)[C@H](C)C)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)CCC2
- Category: Compound
- Molecular Weight: 590.63
- Molecular Formula: C27H38N6O9
Lead Time: 4 - 5 weeks
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