mouse monoclonal IgG1; DDX16 Antibody (24) is an IgG1 mouse monoclonal DDX16 antibody (also designated DHX16 antibody) that detects the DDX16 protein of mouse, rat and human origin by WB, IP and IF. DDX16 Antibody (24) is available as the non-conjugated anti-DDX16 antibody. DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX16 (DEAD-box protein 16), also known as DHX16, DBP2, PRP8 or PRO2014, is a 1,041 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. One of several members of the DEAD-box protein family, DDX16 localizes to the nucleus and is thought to function as an RNA helicase that is involved in pre-mRNA splicing events, playing an important role in cell cycle progression. The gene encoding DDX16 is located on a region of chromosome 6 that is associated with a variety of diseases, including malignancies and genetic mutations, suggesting a possible role for DDX16 in the pathogenesis of certain disorders.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.