CL2-H85D3-20ug CL2-H85D3-100ug
Biotinylated Human Claudin-18.2 Protein, His,Avitag™&Flag Tag (Detergent)
ACROBiosystems
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DESCRIPTION
Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.
DETAILS
- Tag: N-10×His & C-Flag & C-Avi
- Host: InsectCells
- Size: 20ug
- Buffer: 50 mM HEPES, 150 mM Nacl, DDM, CHS, pH7.5
- Format: Liquid
- Purity: 90%
- Source: Biotinylated Human Claudin-18.2 Protein, His,Avitag&Flag Tag (CL2-H85D3) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ala 200 (Accession # P56856-2).
- Storage: -70℃
- Category: MABSol® Biotin Labeled Proteins
- Molecule: Claudin-18.2
- Conjugate: Biotin-labeled
- Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
- Exp Region: Met 1 - Ala 200
- Swiss-prot: P56856-2
- Package Size: 20ug*1
- Characteristics: This protein . The protein has a calculated MW of 26.8 kDa. The protein migrates as 25 kDa,40 kDa and 43-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 26.8 kDa
- Shipping Condition: Dry ice
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html