Anti-SMURF1 Antibody

DESCRIPTION

E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS . Plays a role in dendrite formation by melanocytes .

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: Q9HCE7 Human;SwissProt: Q9CUN6 Mouse
Clonality: Rabbit polyclonal Antibody
Conjugate: Non-conjugated
Alias Names: E3 ubiquitin-protein ligase SMURF1 antibody hSMURF1 antibody KIAA1625 antibody Smad specific E3 ubiquitin ligase 1 antibody SMAD specific E3 ubiquitin protein ligase 1 antibody Smad ubiquitination regulatory factor 1 antibody SMAD-specific E3 ubiquitin-protein ligase 1 antibody SMUF1_HUMAN antibody SMURF 1 antibody smurf1 antibody
Application: WB
Epitope Region: Synthetic peptide within human SMURF1 aa 30-80.
Protein Target: 3 ubiquitin-protein ligase SMURF1 hSMURF1 HECT-type E3 ubiquitin transferase SMURF1 SMAD ubiquitination regulatory factor 1 SMAD-specific E3 ubiquitin-protein ligase 1
Target Species: Human,Mouse,Rat
Species Reactivity: Human,Mouse,Rat