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Recombinant Human Chemerin



Chemerin is a secreted chemoattractant protein that can signal through the chemokine-like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant Human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.


  • Gene Id: 5919
  • Uniprot: Q99969
  • Activity: Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml.
  • Category: RUO Cytokines
  • Subcategory: Growth Factors & Cytokines
  • Research Areas: Chemotaxis, Diabetes/Weight Regulation, Immune System, Lipid Metabolism
  • Alternative Names: Tazarotene-induced gene 2 (TIG2), RARRES2
  • Species of Origin: Human
  • Expression System Source: E.coli