12-9224
Anti-AFP antibody(DMC281), IgG1 Chimeric mAb
Abeomics
DESCRIPTION
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
DETAILS
- App Id: FACS
- Antigen: AFP
- Format Id: Liquid
- Clone Name: DMC281
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Purification: Purified from cell culture supernatant by affinity chromatography
- Reactivity Id: Human
- Alternative Name: AFPD, FETA, HPAFP
- Application Note: FACS 1/100
- Storage Condition: Store at -20°C for 12 months (Avoid repeated freezing and thawing)