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Human Nitric Oxide Synthase, Inducible, INOS-NOS2 ELISA Kit

Bioassay Technology Laboratory


Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed: 7531687, PubMed: 7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed: 25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed: 19688109).


  • GeneID: 4843
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 131,117
  • Synonyms: Hepatocyte NOS;HEP-NOS;Inducible NO Synthase;Inducible NOS;iNOS;Nitric oxide Synthase, inducible;NOS 2;NOS type II;NOS2;Peptidyl-cysteine S-nitrosylase NOS2
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: NOS2
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.11ng/ml
  • Target Protein: NOS2
  • Detection Range: 0.2-60ng/ml
  • Full Product Name: Nitric Oxide Synthase, Inducible
  • Standard Solution: 80ng/ml
  • UniProt Accession: P35228