RP00088
Recombinant Human Trk-A/NTRK1 Protein
ABclonal
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DESCRIPTION
This protein is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
DETAILS
- Tag: C-hFc&His
- Source: HEK293 cells
- Gene Id: 4914
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P04629
- Research Areas: Growth Factor
- Alternative Names: MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA,NTRK1,TRK,TRK1,TRKA,Trk-A,p140-TrkA
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