DESCRIPTION

• Aa: 808-end
• Mw: 42.5 kDa
• Tags: N-terminal His-tag
• Format: Aqueous buffer solution
• Genbank: NM_004972
• Species: Human
• Uniprot: O60674
• Shiptemp: -80°C (dry ice)
• Synonyms: JAK2, Janus kinase-2, Just Another Kinase 2
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Cytoplasmic Tyrosine
• References: 1. Tono,C.,et al., Leukemia 19 (10), 1843-1844 (2005). 2. Goerttler,P.S., et al., Blood 106 (8), 2862-2864(2005).
• Description: Human Jak2 (GenBank Accession No. NM_004972), (a.a. 808-end) with N-terminal His-tag, MW=42.5 kDa, expressed in a baculovirus expression system.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
• Host Species: insect
• Product Type: Protein
• Host Cell Line: Sf9 cells
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: 50 mM HEPES (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 200 µM ATP, 0.01% Brij-35, and 2 µM substrate (Tyr 4, Invitrogen) at room temperature for 1 hour. Developer solution was added to reaction and reaction was stopped after 1 hour of incubation at RT._x000D_
• Related Products: 40451, 75003, 79495, 79772, 78487
• Specific Activity: 118 pmol/min/µg.
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Kinase/Cytoplasmic Tyr