AMG 9810

DESCRIPTION

A competitive antagonist of capsaicin activation of the TRPV1 (IC50s = 24.5 and 85.6 nM for human and rat, respectively); reverses thermal and mechanical hyperalgesia in a rat model of inflammatory pain

DETAILS

Inchi: InChI=1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
Purity: ≥98%
Raptas: Product Type|Biochemicals|Ion Channel Modulation||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Pain Research
Smiles: CC(C)(C)C1=CC=C(/C=C/C(NC2=CC=C(OCCO3)C3=C2)=O)C=C1
Inchikey: GZTFUVZVLYUPRG-IZZDOVSWSA-N
Cas Number: 545395-94-6
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C21H23NO3
Formula Weight: 337.4
Shelf Life Days: 1460