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ILF-C5243-100ug ILF-C5243-1mg

Cynomolgus IL-17F Protein, His Tag

ACROBiosystems

DESCRIPTION

Cynomolgus IL-17F, His Tag (ILF-C5243) is expressed from human 293 cells (HEK293). It contains AA Arg 31 - Gln 163 (Accession # G7P4V0-1).

DETAILS

  • Tag: N-10×His
  • Host: HEK293
  • Size: 100ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Cytokines&Growth Factors
  • Molecule: IL-17F
  • Accession: XP_005552814.1
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Interleukin-17F (IL17F) is also known as Interleukin-24 (IL24), Cytokine ML-1, is a secreted disulfide-linked homodimer which belongs to the IL-17 family. There are at least six members of the IL-17 family in humans and in mice: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25) and IL-17F (also called IL-24). IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F / IL-24 is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL17F / Interleukin-24 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. IL17F / IL-24 stimulates PBMC and T-cell proliferation and Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6).
  • Exp Region: Arg 31 - Gln 163
  • Swiss-prot: G7P4V0-1
  • Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.8 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 0.1 EU per μg
  • Molecular Weight: 16.8 kDa
  • Shipping Condition: RT
  • Species Reactivity: Cynomolgus
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html