Anti-Leucine-rich repeat-containing G-protein coupled receptor 5, LGR5 antibody

DESCRIPTION

Leucine-rich repeat-containing G-protein coupled receptor 5(LGR5), also known as GPR49, is a 907-amino acid 7-transmembrane protein, belongs to G Protein-Coupled Receptor. The differential expression of GPR49 between normal and tumor tissue was significant. GPR49 was upregulated in colon primary tumor tissues. In addition to colon tumors, GPR49 was also found to be upregulated in ovarian primary tumor tissues. Moreover, the expression level of GPR49 in colon and ovarian tumors increased in more advanced tumors suggesting a role for the receptor in tumor progression.

DETAILS

Host: Rabbit
Isotype: IgG
Clonality: Polyclonal
Immunogen: A synthetic peptide (conjugated to KLH) corresponding to the region of LGR5.
Lead Time: 1-2 weeks
SwissProt: O75473
Alias Names: G protein coupled receptor 49, G-protein coupled receptor 49, G-protein coupled receptor 67, GPCR 67, GPR49, G protein coupled receptor 67, FEX, g protein-coupled receptor fex, G-protein coupled receptor HG38, GPR 49, GPR 67, GPR49, GPR67, Leucine rich repeat containing G protein coupled receptor 5, LGR5, HG 38, HG38, LGR5, Leucine-rich repeat-containing G-protein coupled receptor 5, LGR 5, Orphan G protein coupled receptor HG38, antibody
Applications: WB; IHC-P; ICC
Purification: Immunogen affinity purified
Storage Buffer: In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Species Reactivity: Human, mouse
Storage Instruction: Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).