21366
Trifluorothymidine
Cayman Chemical
DESCRIPTION
A derivative of thymidine (Item No. 20519) that exhibits antiviral and anticancer activity by inhibiting thymidylate synthase, thereby blocking nucleic acid synthesis, and by incorporating into DNA, which leads to DNA damage and apoptosis
DETAILS
- Inchi: InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Nucleotides/Nucleosides||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|DNA Damage and Repair||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Infectious Disease|Viral Diseases
- Smiles: O=C(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)NC1=O
- Inchikey: VSQQQLOSPVPRAZ-RRKCRQDMSA-N
- Cas Number: 70-00-8
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C10H11F3N2O5
- Formula Weight: 296.2
- Shelf Life Days: 1460