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HY-112146A

MMG-11 (quarterhydrate)

MedChem Express

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DESCRIPTION

MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].

DETAILS

  • Purity: >98%
  • Smiles: OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1.[1/4].O
  • Category: Reference compound
  • Lead Time: 1-2 days
  • Molecular Weight: 310.78
  • Molecular Formula: C15H14O7.1/4H2O

Lead Time: 1 - 2 weeks

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