Anti-BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) Monoclonal Antibody(Clone: BARX1/2759)

DESCRIPTION

BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog sµggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.

DETAILS

Gene: BARX1
App Id: IHC
Gene Id: 56033
Isotype: Mouse IgG1, kappa
Clone Name: BARX1/2759
Uniprot Id: Q9HU1
Host Animal: Mouse
Clonality Id: Monoclonal
Reactivity Id: Human
Product Content: 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Alternative Name: BarH like homeobox 1; BarX 1; BARX homeobox 1; Homeobox protein BarH like 1
Application Note: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes);
Storage Condition: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Immunogen Information: Recombinant fragment of human BARX1 protein (around aa 155-254) (exact sequence is proprietary)