Cynomolgus CA125 / MUC16 Protein, His Tag (MALS verified)

DESCRIPTION

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Cynomolgus CA125 Protein, His Tag (CA5-C52H8) is expressed from human 293 cells (HEK293). It contains AA Pro 11544 - Pro 12188 (Accession # XP_045234963.1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: CA125
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Pro 11544 - Pro 12188
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.9 kDa. The protein migrates as 95-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 73.9 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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