Human Beta-NGF Protein, premium grade

DESCRIPTION

Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

DETAILS

Tag: Native
Host: HEK293
Size: 20ug
Buffer: 20 mM NaAC, 150 mM NaCl, pH5.5
Format: Powder
Purity: 90%
Source: Human Beta-NGF Protein, premium grade (BEF-H5214) is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Ala 241 (Accession # P01138).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Beta-NGF
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 122 - Ala 241
Package Size: 20ug*1
Characteristics: This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as 14-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.01 EU per μg
Molecular Weight: 13.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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