Recombinant Murine GM-CSF

DESCRIPTION

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues.

DETAILS

Gene Id: 12981
Uniprot: P01587
Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: Cancer, Cell Culture, Immune System, Inflammation, Stem Cells and Differentiation, Wound Healing, COVID-19
Alternative Names: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-alpha
Species of Origin: Murine
Expression System Source: E.coli