Biotinylated Cynomolgus TSLP Protein, His,Avitag™

DESCRIPTION

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 200ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Cynomolgus TSLP, His,Avitag (TSP-C82E3) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # A0A7N9CAT7-1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: TSLP
Accession: XP_005557555.1
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Tyr 29 - Gln 159
Swiss-prot: A0A7N9CAT7-1
Package Size: 200ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 18.8 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 18.8 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html