RP01032
Recombinant Human IL-13RA1/CD213a1 Protein
ABclonal
Image
DESCRIPTION
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. IL13RA1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. This subunit together with IL4RA can form a functional receptor for IL13. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
DETAILS
- Tag: C-His
- Source: HEK293 cells
- Gene Id: 3597
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P78552
- Research Areas: Bio-Markers & CD Antigens,Interleukin
- Alternative Names: CD213A1, CT19, IL-13Ra, NR4,IL13RA1,CT19,IL-13Ra,NR4
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