TC-O 9311

DESCRIPTION

An agonist of GPR139 (EC50 = 39 nM in a calcium mobilization assay); selective for GPR139 over a panel of 90 additional targets; inhibits cell death induced by MPP+, but not 6-OHDA, in primary dopaminergic midbrain neurons at 1 μM

DETAILS

Inchi: InChI=1S/C20H19N3O4/c1-26-15-10-14(11-16(12-15)27-2)19(24)22-23-20(25)21-18-9-5-7-13-6-3-4-8-17(13)18/h3-12H,1-2H3,(H,22,24)(H2,21,23,25)
Purity: ≥98%
Raptas: Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease
Smiles: COC1=CC(OC)=CC(C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)=O)=C1
Inchikey: KPTMSQHTGZMEFU-UHFFFAOYSA-N
Cas Number: 444932-31-4
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C20H19N3O4
Formula Weight: 365.4
Shelf Life Days: 1460