TAU-H51H3-100ug TAU-H51H3-1mg
Human Tau-441 / 2N4R Protein, His Tag
ACROBiosystems
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DESCRIPTION
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.
DETAILS
- Tag: N-10×His
- Host: E. coli
- Size: 1mg
- Buffer: 50 mM Tris, 150 mM NaCl, 1 mM EDTA, pH7.5
- Format: Powder
- Purity: 90%
- Source: Human Tau-441, His Tag (TAU-H51H3) is expressed from E. coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: Tau
- Accession: NP_005901.2
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Met 1 - Leu 441
- Swiss-prot: P10636-8
- Package Size: 250ug*4
- Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE).
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 47.9 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html