Zearalenone

DESCRIPTION

A mycotoxin; binds to human ERα and ERβ (IC50s = 9 and 5.8 nM, respectively); induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs; induces hyperestrogenism in pigs from 1.5-5 mg/kg; has been found as a contaminant in wheat, maize, and barley and livestock feeds

DETAILS

Inchi: InChI=1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1
Purity: ≥98%
Raptas: Product Type|Biochemicals|Lipids|Polyketides||Product Type|Biochemicals|Natural Products|Polyketides||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Toxicology & Xenobiotic Metabolism|Environmental Toxicology|Animal-Based Agriculture||Research Area|Toxicology & Xenobiotic Metabolism|Environmental Toxicology|Plant-Based Agriculture||Research Area|Toxicology & Xenobiotic Metabolism|Organ- & System-Specific Toxicity|Endocrine Disruption||Research Area|Toxicology & Xenobiotic Metabolism|Organ- & System-Specific Toxicity|Reproductive||Research Area|Toxicology & Xenobiotic Metabolism|Toxic Agents|Toxins
Smiles: OC1=C(C(O[C@@H](C)CCCC(CCC/C=C/2)=O)=O)C2=CC(O)=C1
Inchikey: MBMQEIFVQACCCH-QBODLPLBSA-N
Cas Number: 17924-92-4
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C18H22O5
Formula Weight: 318.4
Shelf Life Days: 1460