79506
MCL-1 TR-FRET Assay Kit
BPS Bioscience
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DESCRIPTION
The MCL-1 TR-FRET Assay Kit is designed to measure the inhibition of MCL-1 binding to its ligand in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing terbium-labeled donor, dye-labeled acceptor, MCL-1, peptide ligand, and an inhibitor is incubated for 3 hours. Then, the fluorescence intensity is measured using a fluorescence reader.
DETAILS
- Shiptemp: -80°C (dry ice)
- Synonyms: mcl1
- Warnings: Avoid freeze/thaw cycles.
- Category: Apoptosis/Assay Kit
- References: 1. Abid, M., et al. Curr Med Chem 2017; 24:4488.
- Description: The MCL-1 TR-FRET Assay Kit is designed to measure the inhibition of MCL-1 binding to its ligand in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing terbium-labeled donor, dye-labeled acceptor, MCL-1, peptide ligand, and an inhibitor is incubated for 3 hours. Then, the fluorescence intensity is measured using a fluorescence reader.
- Methodology: TR-FRET
- Unspsc Code: 41121811
- Unspsc Name: Laboratory microchemistry kits
- Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.
- Product Type: Assay Kit
- Biosafety Level: Not applicable (BSL-1)
- Related Products: 50273, 50272, 50222, 50223, 40742
- Storage Stability: At least 6 months from date of receipt when stored as directed.
- Scientific Category: Apoptosis
- Instructions for Use: See assay kit datasheet for detailed protocol.