E6652Hu
Human DNA Topoisomerase 2-alpha, TOP2A ELISA Kit
Bioassay Technology Laboratory
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DESCRIPTION
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166, PubMed:22323612).
May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
DETAILS
- GeneID: 7153
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 174,385
- Synonyms: DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;TOP2;TOP2A;TOP2alpha;TOPIIA;TP2A
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: TOP2A
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 9.78ng/L
- Target Protein: TOP2A
- Detection Range: 20-3800ng/L
- Full Product Name: DNA topoisomerase 2-alpha
- Standard Solution: 4000ng/L
- UniProt Accession: P11388