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Human DNA Topoisomerase 2-alpha, TOP2A ELISA Kit

Bioassay Technology Laboratory


Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166, PubMed:22323612). May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).


  • GeneID: 7153
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 174,385
  • Synonyms: DNA topoisomerase 2-alpha;DNA topoisomerase II, alpha isozyme;TOP2;TOP2A;TOP2alpha;TOPIIA;TP2A
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: TOP2A
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 9.78ng/L
  • Target Protein: TOP2A
  • Detection Range: 20-3800ng/L
  • Full Product Name: DNA topoisomerase 2-alpha
  • Standard Solution: 4000ng/L
  • UniProt Accession: P11388