Mouse CDNF Protein, His Tag (MALS verified)

DESCRIPTION

CDNF is a member of the ARMET family and acts as a trophic factor for dopamine neurons. CDNF inhibits the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the dopaminergic function and inhibits the degeneration of dopaminergic neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 20ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Mouse CDNF, His Tag (CDF-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Leu 187 (Accession # Q8CC36).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: CDNF
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 25 - Leu 187
Swiss-prot: Q8CC36
Package Size: 20ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.4 kDa. The protein migrates as 21-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 20.4 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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