RP00221
Recombinant Human MMP-13 Protein
ABclonal
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DESCRIPTION
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases. MMP-13 (Collagenase-3) has been demonstrated to degrade a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X and XIV, gelatin, aggrecan, perlecan and fibronectin. MMP-13 is proteolytically processed to generate the mature protease. MMP-13 is distinguished from the other human collagenases ,it cleaves type II collagen more efficiently than types I and III. MMP-13 is expressed by fibroblasts, chrondrocytes and squamous epithelial cells. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis.
DETAILS
- Tag: C-His
- Source: HEK293 cells
- Gene Id: 4322
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: P45452
- Research Areas: Other Recombinant Protein
- Alternative Names: CLG3, MANDP1, MDST, MMP-13,MMP13,MANDP1,MDST,MMP-13
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