Human Neurogranin Protein, His Tag

DESCRIPTION

Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.

DETAILS

Tag: N-10×His
Host: E. coli
Size: 100ug
Buffer: 20 mM Tris, 150 mM NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Human Neurogranin, His Tag (NEN-H5144) is expressed from E. coli cells. It contains AA Met 1 - Asp 78 (Accession # Q92686).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Neurogranin
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Met 1 - Asp 78
Swiss-prot: Q92686
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 9.5 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 9.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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