DESCRIPTION

• Mw: 58.8 kDa
• Tag: TurboGFP
• Accn: NM_001289159
• Refseq: NM_001289159.2
• Status: 2 Weeks*
• Symbol: EMR3
• Vector: pCMV6-AC-GFP
• Category: cDNA Clones
• Locus Id: 84658
• Orf Size: 1578 bp
• Synonyms: EMR3
• Refseq Orf: 1581 bp
• Uniprot Id: Q9BY15
• Refseq Size: 2045 bp
• Availability: 2 Weeks
• Cytogenetics: 19p13.12
• Gene Summary: This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
• Sequence Data: ORF Nucleotide Sequence ( show hide ) >RG238723 representing NM_001289159. Blue =ORF Red =Cloning site Green =Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGC C ATGCAGGGACCATTGCTTCTTCCAGGCCTCTGCTTTCTGCTGAGCCTCTTTGGAGCTGTGACTCAGAAA ACCAAAACTTCCTGTGCTAAGTGCCCCCCAAATGCTTCCTGTGTCAATAACACTCACTGCACCTGCAAC CATGGATATACTTCTGGATCTGGGCAGAAACTATTCACATTCCCCTTGGAGACATGTAACGCTATTGAA ACTCAAGCGATTACAGACAATTGCTCTGAAGAAAGAAAGACATTCAACTTGAACGTCCAAATGAACTCA ATGGACATCCGTTGCAGTGACATCATCCAGGGAGACACACAAGGTCCCAGTGCCATTGCCTTTATCTCA TATTCTTCTCTTGGAAACATCATAAATGCAACTTTTTTTGAAGAGATGGATAAGAAAGATCAAGTGTAT CTGAACTCTCAGGTTGTGAGTGCTGCTATTGGACCCAAAAGGAACGTGTCTCTCTCCAAGTCTGTGACG CTGACTTTCCAGCACGTGAAGATGACCCCCAGTACCAAAAAGGTCTTCTGTGTCTACTGGAAGAGCACA GGGCAGGGCAGCCAGTGGTCCAGGGATGGCTGCTTCCTGATACACGTGAACAAGAGTCACACCATGTGT AATTGCAGTCACCTGTCCAGCTTCGCTGTCCTGATGGCCCTGACCAGCCAGGAGGAGGATCCCGTGCTG ACTGTCATCACCTACGTGGGGCTGAGCGTCTCTCTGCTGTGCCTCCTCCTGGCGGCCCTCACTTTTCTC CTGTGTAAAGCCATCCGGAACACCAGCACCTCACTGCATCTGCAGCTCTCGCTCTGCCTCTTCCTGGCC CACCTCCTCTTCCTCGTGGGGATTGATCGAACTGAACCCAAGGTGCTGTGCTCCATCATCGCCGGTGCT TTGCACTATCTCTACCTGGCCGCCTTCACCTGGATGCTGCTGGAGGGTGTGCACCTCTTCCTCACTGCA CGGAACCTGACAGTGGTCAACTACTCAAGCATCAATAGACTCATGAAGTGGATCATGTTCCCAGTCGGC TATGGCGTTCCCGCTGTGACTGTGGCCATTTCTGCAGCCTCCTGGCCTCACCTTTATGGAACTGCTGAT CGATGCTGGCTCCACCTGGACCAGGGATTCATGTGGAGTTTCCTTGGCCCAGTCTGTGCCATTTTCTCT GCGAATTTAGTATTGTTTATCTTGGTCTTTTGGATTTTGAAAAGAAAACTTTCCTCCCTCAATAGTGAA GTGTCAACCATCCAGAACACAAGGATGCTGGCTTTCAAAGCAACAGCTCAGCTCTTCATCCTGGGCTGC ACATGGTGTCTGGGCTTGCTACAGGTGGGTCCAGCTGCCCAGGTCATGGCCTACCTCTTCACCATCATC AACAGCCTCCAAGGCTTCTTCATCTTCTTGGTCTACTGCCTCCTCAGCCAGCAGGTCCAGAAACAATAT CAAAAGTGGTTTAGAGAGATCGTAAAATCAAAATCTGAGTCTGAGACATACACACTTTCCAGCAAGATG GGTCCTGACTCAAAACCCAGTGAGGGGGATGTTTTTCCAGGACAAGTGAAGAGAAAATAT ACGCGT ACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC Protein Sequence ( show hide ) >Peptide sequence encoded by RG238723 Blue =ORF Red =Cloning site Green =Tag(s) MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNAIE TQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINATFFEEMDKKDQVY LNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMC NCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLA HLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVG YGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSE VSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQY QKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY TR TRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• E Coli Selection: Ampicillin (100 ug/mL)
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Restriction Sites: SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Mammalian Cell Selection: Neomycin