HLC-H52H9-25ug HLC-H52H9-200ug
Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Tetramer Protein
ACROBiosystems
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DESCRIPTION
The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*0301 KRASG12C (VVVGACGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVVGACGVGK peptide of the KRASG12C.
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 25ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Tetramer Protein (HLC-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGACGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVVGACGVGK).
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: HLA-A*0301 & B2M & KRASG12C (VVVGACGVGK)
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGACGVGK peptide
- Swiss-prot: P04439 & P61769 & VVVGACGVGK
- Package Size: 25ug*1
- Characteristics: Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Tetramer Protein is assembled by biotinylated monomer (HLC-H82E3) and streptavidin. Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12C peptide. Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 35.9 kDa and 11.7 kDa. The protein migrates as 40-43 kDa, 13 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 35.9 kDa and 11.7 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html