FITC-Labeled Human IL-15 R alpha / CD215 Protein, Fc Tag (MALS verified)

DESCRIPTION

IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 200ug
Buffer: PBS, 0.2 M Arginine, pH7.4
Format: Powder
Purity: 95%
Source: FITC-Labeled Human IL-15 R alpha, Fc Tag (ILA-HF255) is expressed from human 293 cells (HEK293). It contains AA Ile 31-Thr 205 (Accession # Q13261-1).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: IL-15 R alpha
Accession: NP_002180.1
Conjugate: FITC Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ile 31-Thr 205
Swiss-prot: Q13261-1
Package Size: 200ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.8 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 44.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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