Human CCL7 / MCP-3 Protein, His Tag

DESCRIPTION

CCL7, also known as monocyte chemotactic protein-3 (MCP-3), is a CC (cysteine–cysteine) chemokine that is 11–18 kDa in size depending on the level of glycosylation. Its gene has been mapped to chromosome 17q11.2-q12 and is expressed in response to endogenous cytokines or exogenous bacterial products. This protein shares 60–71% homology with MCP-1 and MCP-2 chemokines and consequently binds similar receptors. Receptors CCR1, CCR2, CCR3, and CCR5 have been identified to bind CCL7 in both progenitor and immune cells.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human CCL7, His Tag (CC7-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Leu 99 (Accession # P80098-1).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: CCL7
Accession: NP_006264.2
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 24 - Leu 99
Swiss-prot: P80098-1
Package Size: 1mg*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.8 kDa. The protein migrates as 14 kDa and 18-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 10.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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