Biotinylated Human IL-3 R alpha / CD123 Protein, Avitag™ (MALS verified)

DESCRIPTION

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

DETAILS

Tag: C-Avi
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Human IL-3 R alpha Protein, Avitag (ILA-H8214) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: IL-3 R alpha
Accession: NP_002174.1
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Thr 19 - Arg 305
Swiss-prot: P26951-1
Package Size: 25ug*1
Characteristics: This protein carries an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 35.3 kDa. The protein migrates as 53-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 35.3 kDa
Shipping Condition: RT
Species Reactivity: Human
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