T37604
ITK inhibitor
TargetMol
DESCRIPTION
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminomethyl)benzamide) is the analogue of BMS-509744, which can potently and selectively inhibit Itk kinase activity.
DETAILS
- Cas: 439574-61-5
- Purity: 98%
- Smiles: C(=O)(C1=C(OC)C=C(C)C(SC=2SC(NC(=O)C3=CC=C(CNC(C(C)C)C)C=C3)=NC2)=C1)N4CCN(C(C)=O)CC4
- Category: Compound
- Molecular Weight: 609.8
- Molecular Formula: C31H39N5O4S2
Lead Time: 4 - 5 weeks
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