mouse monoclonal IgG1; nm23-H7 Antibody (B-9) is an IgG1 κ mouse monoclonal nm23-H7 antibody (also designated nm23-H7 antibody) that detects the nm23-H7 protein of mouse, rat and human origin by WB, IP, IF and ELISA. nm23-H7 Antibody (B-9) is available as both the non-conjugated anti-nm23-H7 antibody form, as well as multiple conjugated forms of anti-nm23-H7 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid protein that contains one DM10 domain and belongs to the NDK family. Using magnesium as a cofactor, nm23-H7 functions to catalyze the ATP-dependent creation of nucleoside triphosphates, thereby playing an essential role in metabolic pathways throughout the body. The gene encoding nm23-H7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.