UPK1B Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 7348
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: UPK1B
Other Names: Uroplakin-1b, UP1b, Tetraspanin-20, Tspan-20, Uroplakin Ib, UPIb, UPK1B, TSPAN20
Availability: 2 weeks
Bio Background: The protein encoded by this gene is a member of thetransmembrane 4 superfamily, also known as the tetraspanin family.Most of these members are cell-surface proteins that arecharacterized by the presence of four hydrophobic domains. Theproteins mediate signal transduction events that play a role in theregulation of cell development, activation, growth and motility.This encoded protein is found in the asymmetrical unit membrane(AUM) where it can form a complex with other transmembrane 4superfamily proteins. It may play a role in normal bladderepithelial physiology, possibly in regulating membrane permeabilityof superficial umbrella cells or in stabilizing the apical membranethrough AUM/cytoskeletal interactions. The use of alternatepolyadenylation sites has been found for this gene. [provided byRefSeq].
Bio References: Kalma, Y., et al. Fertil. Steril. 91(4):1042-1049(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Cowled, P., et al. Neoplasia 7(12):1091-1103(2005)Varga, A.E., et al. Neoplasia 6(2):128-135(2004)Tu, L., et al. Mol. Biol. Cell 13(12):4221-4230(2002)
Primary Accession: O75841